Applied mathematics researchers warn of 'triple whammy' drug combination

Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research.

Diuretics and RSA inhibitors are commonly prescribed together for people with hypertension and are available under various pharmaceutical brand names. Painkillers such as ibuprofen are available over-the-counter in most pharmacies and stores in popular brands.

“It’s not that everyone who happens to take this combination of drugs is going to have problems,” said Anita Layton, professor of applied mathematics and Canada 150 Research Chair in mathematical biology and medicine. “But the research shows it’s enough of a problem that you should exercise caution.”

Read more in the feature article on Waterloo News.